Article/Poster

2023.04.20

Healios UDC-derived otic neural progenitor cells demonstrate enhanced survival after transplantation into the cochlea: Northwestern University publication

A research team led by Dr. A.J. Matsuoka of Northwestern University (Chicago, IL, USA) has confirmed that otic neural progenitor cells differentiated from UDCs, new therapeutic products using Universal
Donor Cells (“UDCs”), which are next-generation iPS cells created with gene-editing technology that have a reduced risk of immune rejection regardless of a patient’s HLA type produced by Healios, showed enhanced survival after transplantation into the cochlea compared to otic neural progenitor cells differentiated from an unmodified parental cell line. Healios is pleased to announce that a paper on this research has been published in Stem Cell Research & Therapy, a scientific and academic research journal.

 

Title: Enhanced survival of hypoimmunogenic otic progenitors following intracochlear xenotransplantation: repercussions for stem cell therapy in hearing loss models