Development Status

【Ophthalmology Area】

Development Code	Indication	Market	Pre-clinical test	Clinical test	Apply-approve	On the Market	Progress Status
HLCR011	Wet AMD	Japan	Transplantation conducted under Clinical research(*1)				Undergoing preparation for clinical trial

Development Code	Indication	Market	Pre-clinical test	Phase I Trial	Phase II Trial	Phase III Trial	Apply-approve	On the Market	Progress Status
HLCR012	Dry AMD	US							CRADA with NEI
HLCR012	Dry AMD	EU							Global trial under consideration based on US phase III trial

1. “Clinical research of transplantation of induced pluripotent stem cells – derived retinal pigment epithelium (RPE) cells for exudative age-related macular degeneration (AMD)” conducted by RIKEN etc.

【Liver Disease】

Development Code	Indication	Market	Pre-clinical test	Clinical test	Apply-approve	On the Market	Progress Status
HLCL041	Metabolic Liver Disease	Japan					ONL established