Article/Poster

2024.07.03

Academic paper on Healios UDC in “Stem Cell Research and Therapy” Hypoimmunogenic human iPSCs expressing HLA-G, PD-L1, and PD-L2 evade innate and adaptive immunity

The researchers at Healios have published a recent work revealing that hypoimmunogenic human iPSCs, which have diminished the expression of polymorphic HLA molecules and forced the expression of HLA-G, PD-L1, and PD-L2, can evade both innate and adaptive immunity. This work has been published in the peer-reviewed journal “Stem Cell Research & Therapy”.

 

Title: Hypoimmunogenic human iPSCs expressing HLA-G, PD-L1, and PD-L2 evade innate and adaptive immunity